NAD+ supplements can they really turn back the clock?
If you keep up with the latest health trends, chances are you’ve heard of NAD.
NAD is more than a wellness trend. It is a vital energy-producing coenzyme. Every cell in your body contains it. However, natural NAD levels decline with age. That is why many people turn to supplementation.
What is NAD+?
NAD+ is a crucial coenzyme found in our cells. It plays a major role in regulating cellular functions, neuroprotection, DNA repair and anti-ageing. “If you have high levels of NAD+, it means you will have lots of cellular energy, your cells will function optimally, and you will feel more energetic and alert,” says Conlon. It also means your body can repair itself quicker, which helps keep your organs, including your skin, in good health.

Do we need to supplement our NAD+ levels?
As we age, our NAD+ levels decline – halving every 20 years from birth. And as they do so energy production and cellular repair decrease, “leading to many of the common complaints associated with ageing such as wrinkles, loss of energy and brain fog,” says Conlon.
“Scientists have demonstrated that boosting NAD+ back to youthful levels can rejuvenate old cells back to a state of youth, leading to multiple beneficial effects against ageing and age-related disease,” she continues. Supplements, including IV therapy, can boost NAD+ levels, and certain lifestyle changes may help slow down the decline of NAD+.
Do NAD+ supplements actually work?
Although there are no large-scale clinical trials on humans yet, there is promising research that suggests NAD+ supplementation may have several health benefits. Below, we outline the key ones:
- Increased alertness and energy: “One of the most notable benefits of boosting NAD+ is an improvement in both physical and mental energy,” says Conlon. “Meaning increased endurance, better cognitive function and reduced brain fog.”
- Improved sleep: Sleep also improves as, according to Conlon, NAD+ can help regulate your circadian rhythm which ensures you get quality restorative sleep. One 2022 Study found that after 12-weeks of supplementing NMN (one of the precursors of NAD), fatigue improved in older adults.
- Enhanced recovery: Boosting NAD+ reserves not only improves physical energy but also aids muscle recovery after exercise. This benefit explains why several athletes choose to receive regular NAD+ IV therapy.
- Hair and nail growth: Some supplement users have seen an improvement in the health of their hair and nails. “This is because when your cellular health improves, the body invests more resources into these less important areas of our biology,” explains Conlon.
- Collagen regeneration: If you want to boost skin health, then you need to improve your cellular health. “And this is exactly what NAD+ does,” says Conlon. Collagen loss causes wrinkles. People have long used supplements and creams to replace it. However, protecting collagen-producing cells is now key. Boosting NAD+ has been shown to achieve this effectively.
But while the benefits appear manifold, what of any drawbacks?
Current evidence suggests that most people tolerate NAD+ supplements well, and no major adverse effects have been reported. However, researchers are still studying the long-term and high-dose use of these supplements.
As Angelova notes, clinics typically administer NAD+ IV therapy slowly to minimize temporary side effects like muscle cramping or nausea, which usually pass within 10 minutes.
Treeday NAD+ Advanced – NAD+Supplement for Energy & Healthy Aging -500mg per Serving -60 Count (30 Day Supply)
Repairs DNA
Supports Healthy Aging
Boosts Enegy Levels
Mental Clarity
Supports Metabolism
500 in stock
